Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

Purpose

The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.

Condition

  • Colorectal Cancer

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Known or suspected colorectal adenocarcinoma (Stage I to IVA disease) - Planning to undergo or has undergone a surgical resection for suspected adenocarcinoma of the colon or rectum with curative intent. - 18 years old or older - Willing and able to provide informed consent - Willing to have additional blood samples collected during routine surveillance visits

Exclusion Criteria

  • Not willing to have additional blood samples collected - Pathology that is not consistent with colorectal adenocarcinoma

Study Design

Phase
Study Type
Observational
Observational Model
Case-Only
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Participants with stage I-IV colorectal cancer (CRC) This protocol will include participants with stage I-IV CRC who are scheduled to undergo or have undergone a surgical resection with curative intent.
  • Other: Observation
    No intervention

Recruiting Locations

Washington University in St. Louis and nearby locations

Washington University School of Medicine
St Louis 4407066, Missouri 4398678 63110
Contact:
Mary Pecoraro
314-273-0884
mpecoraro@wustl.edu

More Details

NCT ID
NCT05234177
Status
Recruiting
Sponsor
Tempus AI

Study Contact

CRC Surveillance Study
(833) 514-4187
gemini-crc@tempus.com